About this trial
The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are:
Does ejaculation within 36 hours before surgery reduce seminal vesicle size compared to abstinence of 72 hours or more?
Does seminal vesicle size affect the ease or difficulty of surgical dissection during radical prostatectomy?
Researchers will compare an ejaculation group to an abstinence group to see if seminal vesicle volume and intraoperative surgical parameters differ between them.
Participants will:
Follow specific instructions to either ejaculate or abstain before surgery
Undergo a transrectal ultrasound (TRUS) to measure seminal vesicle size after anesthesia but before surgery
Have their surgical dissection time and difficulty rated by the operating surgeon
Eligibility criteria
Qualifiers
Male patients aged 18 years or older
Histologically confirmed prostate cancer
Scheduled for radical prostatectomy
Able and willing to comply with assigned ejaculation or abstinence protocol
Disqualifiers
Prior bilateral seminal vesicle resection or congenital absence of seminal vesicles
Anatomical abnormalities preventing SV identification
Hormone therapy within 6 months before surgery
Inability to recall ejaculation history in the past 3 days
Trial design
Treatments tested in this trial
- Recent Ejaculation
- Preoperative Abstinence