Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-28
SponsorUniversity Children's Hospital Basel

About this trial

Electrical impedance tomography (EIT) enables assessment of regional lung ventilation at the bedside. EIT has been safely used in newborn infants to image intrathoracic lung volume patterns as early as from the first minute of life. This prospective single-centre observational study is to identify optimal PEEP in infants on respiratory support by measurements of EIT, FOT and SOPI.

Eligibility criteria

Qualifiers

22+0 to 41+6 weeks' gestational age

Requiring mechanical ventilation

Written informed parental consent

Disqualifiers

Major congenital malformations including lung and cardiac malformations

Infants on high frequency oscillatory ventilation

Lack of written informed parental consent

Trial design

Treatments tested in this trial

  • Electrical impedance tomography (EIT)
  • Forced oscillation technique (FOT)
  • Saturation oxygenation pressure index (SOPI)

Treatment groups

86 Participants
are divided into 2 treatment groups