Electrical Impedance Tomography-Guided Identification of the Optimal Lateral Position in Postoperative ARDS
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRuijin Hospital
About this trial
This prospective, randomized crossover physiological study evaluates the effects of lateral positioning (left lateral position and right lateral position) versus the supine position on ventilation-perfusion (V/Q) matching in adult postoperative abdominal surgery participants with acute respiratory distress syndrome (ARDS). Bedside electrical impedance tomography (EIT) will be used to quantify regional ventilation and perfusion (perfusion derived from an intravenous tracer bolus administered during a brief breath-hold) and to calculate global "normal V/Q" (normal V/Q, %). Oxygenation, respiratory mechanics (when applicable), and hemodynamics will be recorded concurrently. Feasibility and safety of the positioning protocol will also be assessed.
Eligibility criteria
Qualifiers
Age ≥18 years
Postoperative abdominal surgery patients admitted to the ICU with ARDS (Berlin definition)
Considered able to tolerate protocolized position changes by the treating team
EIT belt placement and protocol procedures feasible
Disqualifiers
Contraindication to lateral positioning (e.g., unstable spine, uncontrolled bleeding, open abdomen, high-risk surgical wound condition)
Severe hemodynamic instability or other conditions making participation unsafe
High risk of airway/vascular line/drain dislodgement not manageable
Pregnancy
Trial design
Treatments tested in this trial
- Positioning Intervention
Treatment groups
24 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov