Electroacupuncture for the Treatment of Agitated Symptoms of Alzheimer's Disease

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorGuang'anmen Hospital of China Academy of Chinese Medical Sciences

About this trial

The purpose of this study is to evaluate the efficacy of electroacupuncture in the treatment of agitation symptoms in patients with Alzheimer's disease (AD). Meanwhile the study aims to explore the brain central mechanism of electroacupuncture in the treatment of agitation symptoms in patients with AD by using resting state functional magnetic resonance technology.

Eligibility criteria

Qualifiers

Meet the revised draft diagnostic criteria for Alzheimer's disease published by the Alzheimer's Association in 2023

Meet the 2023 IPA definition of agitated symptoms of cognitive impairment

Cohen Mansfield Agitation Inventory (CMAI)≥45 points

Have been on stable anti-AD medication (cholinesterase inhibitors, etc.) for more than 1 month

Disqualifiers

There are contraindications for acupuncture treatment, such as the tendency of acupoint bleeding or allergy to metal

Received electroacupuncture treatment in the past 2 weeks

At the time of the screening, participants are participating in other clinical trials or planned to participate in other clinical trials in the next 17 weeks.

Trial design

Treatments tested in this trial

  • Electroacupuncture group
  • Micro-acupuncture group

Treatment groups

224 Participants
are divided into 2 treatment groups