About this trial
The purpose of this study is to evaluate the efficacy of electroacupuncture in the treatment of agitation symptoms in patients with Alzheimer's disease (AD). Meanwhile the study aims to explore the brain central mechanism of electroacupuncture in the treatment of agitation symptoms in patients with AD by using resting state functional magnetic resonance technology.
Eligibility criteria
Qualifiers
Meet the revised draft diagnostic criteria for Alzheimer's disease published by the Alzheimer's Association in 2023
Meet the 2023 IPA definition of agitated symptoms of cognitive impairment
Cohen Mansfield Agitation Inventory (CMAI)≥45 points
Have been on stable anti-AD medication (cholinesterase inhibitors, etc.) for more than 1 month
Disqualifiers
There are contraindications for acupuncture treatment, such as the tendency of acupoint bleeding or allergy to metal
Received electroacupuncture treatment in the past 2 weeks
At the time of the screening, participants are participating in other clinical trials or planned to participate in other clinical trials in the next 17 weeks.
Trial design
Treatments tested in this trial
- Electroacupuncture group
- Micro-acupuncture group