EP-SCOPE is a prospective, multicentric, non-randomized pilot study that aims to estimate the risk of life-threatening ventricular arrhythmia through use of advanced electrophysiological studies in patients with ischemic or non-ischemic cardiomyopathy with left ventricular ejection fraction (LVEF) \<50% and risk factors of ventricular arrhythmia, otherwise not considered for implantation of an implantable cardioverter defibrillator (ICD).
The objective is to assess the effectiveness of a risk stratification strategy based on detailed electrophysiological exploration of the left ventricle and programmed ventricular stimulation.
Patient with cardiomyopathy with 35%<LVEF<50% and at least one risk factor
Patients with cardiomyopathy with LVEF≤35% and an indication for cardiac resynchronisation
Patients who are minors or aged 80 or over
Patients with unstable coronary artery disease
Myocardial infarction less than 40 days old
Coronary revascularisation <90 days