Electrostimulation Study for Ocular Graft vs. Host Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZhonghui K. Luo, MD, PhD
About this trial
This trial is testing to see if electrostimulation treatment (ET) will be effective in treating those with ocular Graft vs. Host Disease.
Eligibility criteria
Qualifiers
Diagnosis of chronic ocular graft vs. host disease (oGVHD) (ICCGVHD criteria probable or definite)
OSDI score of 22 or higher
NEI corneal staining score (or modified NEI score) of 2 or higher.
Disqualifiers
Patients with any open wound on the eyelid.
Patient with any active cornea ulcer, dacryocystitis, hordeolum, filamentary keratitis, uveitis, retinal detachment, uncontrolled glaucoma or other active pathology per PI's discretion.
Patient with a pacemaker or ICD.
Patient currently pregnant or with a potential to be pregnant during the study.
Trial design
Treatments tested in this trial
- Electrodes with Currents
- Electrodes without Currents
Treatment groups
15 Participants
are divided into 2 treatment groupsSponsors and collaborators
Zhonghui K. Luo, MD, PhD
Lead sponsor
Massachusetts Eye and Ear Infirmary
Sponsor institution
Source ClinicalTrials.gov