About this trial
This study will try to elucidate the neural responses of neonatal patients to surgery-level propofol infusions during induction and maintenance of anesthesia. The main objective is to elucidate the EEG patterns of neural activity that can reliably reflect the level of hypnotic depth in full term neonates undergoing propofol anesthesia based on the classification of EEG into states and the characterization of discrete neonatal EEG events.
Eligibility criteria
Qualifiers
Full term neonates (37 - 42 weeks of gestational age)
Require general anesthesia/deep sedation during their first 28 days of life because they require a surgery or a specific procedure (cardiac or non-cardiac)
Scheduled for propofol induction
Disqualifiers
Neurological surgeries
Perinatal asphyxia
Evidence of neurological injury or pathology
Suspected brain malformations
Trial design
Treatments tested in this trial
- Not listed