Elucidating the Neural Correlates of Anesthesia-induced Unconsciousness in Neonates

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 28
SponsorPontificia Universidad Catolica de Chile

About this trial

This study will try to elucidate the neural responses of neonatal patients to surgery-level propofol infusions during induction and maintenance of anesthesia. The main objective is to elucidate the EEG patterns of neural activity that can reliably reflect the level of hypnotic depth in full term neonates undergoing propofol anesthesia based on the classification of EEG into states and the characterization of discrete neonatal EEG events.

Eligibility criteria

Qualifiers

Full term neonates (37 - 42 weeks of gestational age)

Require general anesthesia/deep sedation during their first 28 days of life because they require a surgery or a specific procedure (cardiac or non-cardiac)

Scheduled for propofol induction

Disqualifiers

Neurological surgeries

Perinatal asphyxia

Evidence of neurological injury or pathology

Suspected brain malformations

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

64 Participants
are grouped into 1 trial group

Locations

This trial has no locations