Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age. PMDD is characterised by recurring emotional, behavioural, cognitive, and somatic symptoms that arise during the luteal (premenstrual) phase of the menstrual cycle and remit shortly after the onset of menses. Although pharmacological interventions are available, many women experience residual symptoms, discontinue treatment or refrain from them because of side effects. Therefore, non-pharmacological treatment options are needed.
Preliminary evidence suggests that internet-delivered cognitive behavioural therapy (ICBT) is a promising candidate, but further research is warranted. Also, there is room for treatment improvement. Specifically, it has been suggested that components targeting emotional and interpersonal dysregulation should be incorporated into CBT for PMDD. The current study aims to assess the effects of an ICBT intervention for PMDD incorporating skills training in emotion regulation and interpersonal effectiveness in a randomised controlled trial (RCT).
PMDD diagnosis according to DSM-5
Menstrual cycle length between 23-34 days, i.e., 5-8 cycles in the last six months
Sufficient proficiency in Swedish to comprehend the treatment materials
Access to computer/tablet/mobile phone with internet connection
Breastfeeding or pregnancy during the previous three months
Initiation of or change in treatment with antidepressants, benzodiazepines, contraceptives, or hormones during the last three months
Current or history of a gynaecological disease (e.g., endometriosis, polycystic ovary syndrome) that may confound the results
Ongoing or previous psychological treatment for premenstrual disorders
Uppsala University
Lead sponsor
Friedrich-Alexander-Universität Erlangen-Nürnberg
Collaborator
Utah State University
Collaborator
Linkoeping University
Collaborator