About this trial
The purpose of this study is to determine if the use of emotional sound as subject own name (SON) pronounced by a familiar voice (FV) compared to SON pronounced by a non-familiar voice (NFV) during event related potential (ERP) produced a more reliable neurophysiological P300 responses, and to assess the prognostic value of this P300 responses induced by the SON with a FV.
Eligibility criteria
Qualifiers
patients hospitalized in ICU for cardiac arrest, stroke, subarachnoid haemorrhage or head trauma,
persistent disorder of consciousness (DoC) 12 hours after sedation weaning or patient who has benefited from a prognostic assessment for persistent DoC and who has had in this assessment an evaluation by late PEA with MMN and P300 responses only to neutral sounds ("beep" and patient's first name pronounced by an unfamiliar voice) there is more than 6 months (since April 2022)
Disqualifiers
Moribund patient
Uncontrolled Shock during the neurophysiological evaluation
Sedated patient
Minor patient
Trial design
Treatments tested in this trial
- Use of "expressive" sounds
- Having benefited from a prognostic evaluation by event related potentials (without sound research methods, only neutral sounds)
Treatment groups
Sponsors and collaborators
Assistance Publique - Hôpitaux de Paris
Lead sponsor
URC-CIC Paris Descartes Necker Cochin
Collaborator