End-Tidal Oxygen for Intubation in the Emergency Department
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSydney Local Health District
About this trial
Rapid Sequence Intubation (RSI) is a high-risk procedure in the emergency department (ED). Patients are routinely preoxygenated (given supplemental oxygen) prior to RSI to prevent hypoxia during intubation. For many years anaesthetists have used end-tidal oxygen (ETO2) levels to guide the effectiveness of preoxygenation prior to intubation. The ETO2 gives an objective measurement of preoxygenation efficacy. This is currently not available in most EDs.
This trial evaluates the use of ETO2 on the rate of hypoxia during intubation for patients in the ED.
Eligibility criteria
Qualifiers
The patient is located in the ED resuscitation bay of the participating centre.
The planned procedure is orotracheal intubation using a laryngoscope and RSI technique with preoxygenation for patients who are spontaneously breathing.
Any patient requiring any form of oxygen therapy before preoxygenation.
Pneumonia, pulmonary oedema, acute respiratory distress syndrome (ARDS), aspiration, pulmonary contusion from trauma, infective exacerbations of known lung disease (e.g. asthma, pulmonary fibrosis, emphysema) or pulmonary embolism (PE)
Disqualifiers
Patient is known to be less than 18 years old.
The patient has a supraglottic device in-situ e.g iGel or LMA.
The patient is known to be pregnant.
The patient is known to be a prisoner.
Trial design
Treatments tested in this trial
- End-tidal oxygen monitor
Treatment groups
1,400 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov