Endometriosis and Migraine

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age12-45
SponsorWashington University School of Medicine

About this trial

This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls. Participants will complete surveys, experimental pain paradigms and collection of samples for hormone analyses.

Eligibility criteria

Qualifiers

Patients with diagnosed endometriosis, migraine, or both endometriosis and migraine

Healthy control subjects with no history of chronic pain

Age 12-45

Assigned female sex at birth

Disqualifiers

Pregnancy or breastfeeding

Presence of prolactinoma

Presence of psychiatric, neurological, endocrinological and/or developmental conditions and taking medications for these conditions

Current use of dopamine agonist or SSRI medications

Trial design

Treatments tested in this trial

  • Thermal stimuli
  • Pressure stimuli
  • Pain ratings
  • Conditioned pain modulation (CPM) response
  • Hormonal assessment

Treatment groups

120 Participants
are divided into 4 treatment groups