About this trial
Pediatric obstructive sleep apnea (OSA) can lead to severe health issues if untreated. While polysomnography is the gold standard for diagnosis, current surgical treatment in Denmark relies on caregiver reports and clinical exams. Approximately 25% of patients have persistent symptoms post-surgery, indicating the need for better diagnostic and treatment options. Drug-Induced Sleep Endoscopy (DISE) allows dynamic upper airway visualization during mild sedation, aiding in treatment decisions. This research project aims to evaluate the impact of DISE-guided interventions on pediatric OSA outcomes and compare its effectiveness and cost/benefit with traditional diagnostic approaches.
Eligibility criteria
Qualifiers
Surgically naïve, otherwise healthy, non-syndromic children aged 2-12 years with suspected oSDB of any severity
One completed Pediatric Sleep Questionnaire - Sleep Related Breathing Disorder (PSQ)
Home Respiratory Polygraphy (HRP) and/or in-house Polysomnography (PSG) showing OSA according to the definition of AAO-HNSF
Disqualifiers
Syndromes and congenital/acquired craniofacial abnormalities/malformations of the upper airways
Neurological conditions affecting upper airway muscle tone
Lower airway disease (tracheomalacia, asthma)
Previous surgery of the nose/pharynx/larynx
Trial design
Treatments tested in this trial
- Drug-induced Sleep Endoscopy findings (identified obstruction sites)
Treatment groups
Sponsors and collaborators
Regional Hospital West Jutland
Lead sponsor
University Hospital, Antwerp
Collaborator