Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40+
SponsorUniversity Hospital, Basel, Switzerland
About this trial
The aim of this single-center, two-arm, open-labeled, randomized controlled clinical study is to compare two surgical interventions, endoscopic third ventriculostomy and ventriculoperitoneal shunt, in treating idiopathic normal pressure hydrocephalus in terms of clinical improvement.
Eligibility criteria
Qualifiers
>40 years of age
Symptom duration ≥3 months, <24 months
No antecedent head trauma, ICH, meningitis, or other cause of secondary hydrocephalus
MUST show gait/balance disturbance, PLUS cognition impairment AND/OR urinary dysfunction.
Disqualifiers
≤40 years of age
No informed consent
Other neurologic, psychiatric or general medical condition which is sufficient to explain the presenting symptoms.
Previous cranial neurosurgical interventions
Trial design
Treatments tested in this trial
- Endoscopic third ventriculostomy (ETV)
- Ventriculoperitoneal shunt (VPS)
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov