About this trial
This is a single-center prospective pilot study in patients with symptomatic partially obstructing intestinal strictures without severe active inflammation or penetrating complications, evaluating the use of LAMS with respect to symptom and quality of life improvement and the development of stent-related complications.
Eligibility criteria
Qualifiers
≥18 years of age
Established Diagnosis of inflammatory bowel disease
Symptomatic, single, fibrostenotic or anastomotic stricture <6 cm in length without severe active inflammation, pre-stenotic intestinal fistula or penetrating complication, and within reach of the adult colonoscope (colon or terminal ileum)
Ability to accurately gauge stricture length with imaging and safely deploy the stent using conventional fluoroscopic techniques
Disqualifiers
More than one intestinal stricture
Stricture out of reach of standard adult colonoscope
High-grade stricture (complete or near complete bowel obstruction
Severe active inflammation in the stricture or associated penetrating complication, including fistula, inflammatory phlegmon or abscess
Trial design
Treatments tested in this trial
- Endoscopically placed lumen-apposing metal stents for the treatment of IBD-strictures