Endothelial Colony-Forming Cells in Patients With VWD, AVWS and Healthy Subjects

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16+
SponsorFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

About this trial

The goal of this observational study is to learn how endothelial colony-forming cells (ECFCs) behave in people with von Willebrand disease (VWD), acquired von Willebrand syndrome (AVWS), and in healthy individuals.

Eligibility criteria

Qualifiers

No prior diagnosis of VWD, bleeding disorders, or thrombotic disorders.

Willingness to donate blood for study procedures.

Ability and willingness to provide written informed consent.

Age ≥ 18 years.

Disqualifiers

Pregnancy.

Anemia, as determined at screening or based on medical history.

Trial design

Treatments tested in this trial

  • Blood sample collection for VWF measurements in plasma
  • Blood sample collection for ECFC isolation and characterization
  • Genetic testing of VWF

Treatment groups

48 Participants
are divided into 2 treatment groups