Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease
ConditionPAD
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZhongda Hospital
About this trial
Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs. Endovascular arterial denervation (ED) is a minimally invasive technique which could deliver Radiofrequency energy by a multi-electrode catheter to the Lower limb artery to restore Sympathetic activity. The purpose of this study is to evaluate the effects of multi-electrode radiofrequency ablation system on lower limb ischemia with PAD.
Eligibility criteria
Qualifiers
eligible subjects aged 18-75 years,
clinically confirmed PAD patients in Rutherford category II-VI.
Disqualifiers
thrombolytic therapy performed within 30 days,
patients who had undergone vascular bypass surgery before this study,
allergy or contraindication of antiplatelet drugs, anticoagulants, thrombolytic drugs and contrast agents,
patients with obvious bleeding tendency, coagulation dysfunction, hypercoagulability and blood system diseases,
Trial design
Treatments tested in this trial
- endovascular denervation
- PTA
Treatment groups
54 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov