Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorWen-huo Chen
About this trial
Explore the effectiveness and safety of emergency endovascular treatment in patients with mild ischemic stroke due to acute large vessel occlusion in the anterior circulation, identified through perfusion imaging.
Eligibility criteria
Qualifiers
Age 18-80 years old;
Symptoms onset or last known well to randomization is within 24 hours.
Clinical diagnosis of acute ischemic stroke due to anterior circulation intracranial large vessel occlusion (LVO) (including intracranial internal carotid artery [ICA], middle cerebral artery [MCA] M1 segment, MCA M2 segment, with or without ipsilateral extracranial ICA occlusion) confirmed on Computerized tomography angiography (CTA) or Magnetic resonance imaging angiography (MRA) ;
Baseline NIHSS score <6 before randomization (including cases with NIHSS ≥6 at onset but improves before randomization);
Disqualifiers
Premorbid Rankin Scale (mRS) score ≥ 1;
Known allergy to iodine, heparin, anaesthesia, or other definite contraindication to receiving endovascular treatment (EVT) procedure;
Patient has severe or fatal co-morbidities that could interfere with outcome assessments and follow-up (such as malignant tumor, severe heart failure, or renal failure, or life expectancy less than 6 months);
Poorly controlled hypertension (systolic blood pressure >220 mmHg or diastolic blood pressure >120 mmHg);
Trial design
Treatments tested in this trial
- EVT
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Wen-huo Chen
Lead sponsor
Zhangzhou Municipal Hospital
Sponsor institution
Source ClinicalTrials.gov