Engineering Immune Organoids to Study Pediatric Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 25
SponsorGustave Roussy, Cancer Campus, Grand Paris

About this trial

To engineer immune organoids from pediatric patient tissues using induced-pluripotent stem cells (iPSC)

Eligibility criteria

Qualifiers

Age at diagnosis ≤ 25 years except for patients with malignant gliomas and renal tumors for whom no upper age limit is applied

Brain tumors

Renal tumors

Neuroblastoma

Disqualifiers

Any histology not mentioned in the inclusion criteria

Adult patient or parents/guardians incapable/incapable of giving its/their consent

Patients deprived of their liberty by a judicial or administrative decision

Trial design

Treatments tested in this trial

  • Skin biopsy
  • Fresh tumor sample
  • Blood sample
  • Healthy tissue from the tumor
  • Spinal cerebrospinal fluid (SCF)

Treatment groups

108 Participants
are divided into 1 treatment group