A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).
Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
Planned use of regional anesthesia
Ability to follow study protocol
English speaking (secondary outcomes include questionnaires validated in English only)
Hepatic or renal insufficiency
Younger than 18 years old or older than 65 years ol
Patients undergoing general anesthesia
Allergy or intolerance to one of the study medications