Enhancing Language Function in Primary Progressive Aphasia

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age45-80
SponsorUniversity of Arizona

About this trial

This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.

Eligibility criteria

Qualifiers

diagnosed with PPA by neurologist or speech-language pathologist

speech-language deficit arising from PPA

native speaker of English Language or equivalent

adequate vision (normal or corrected to normal)

Disqualifiers

meeting (Diagnostic and Statistical Manual) DSM-IV criteria for Axis I mood, anxiety, psychotic or substance abuse disorders.

highly magnetizable metallic implants, including certain dental work

neurological disorders besides the ones of interest for the study (e.g., epilepsy)

Multiple Sclerosis

Trial design

Treatments tested in this trial

  • tDCS + language therapy
  • sham TDCS + language therapy

Treatment groups

20 Participants
are divided into 2 treatment groups

Sponsors and collaborators