Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorSilvia Brem

About this trial

This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning. Adult participants with a range of reading abilities will receive transcranial random noise stimulation (tRNS) while they perform an artificial orthography learning task. This task simulates letter-speech sound learning, an important first step during reading acquisition known to be impaired in individuals with developmental dyslexia. The effects of the intervention will be assessed using both behavioral measures and functional magnetic resonance imaging (fMRI).

Eligibility criteria

Qualifiers

Age 18-35

All genders

Written informed consent by the participant

German speaking (native)

Disqualifiers

Diagnoses of neurological disorders, intellectual disabilities, or psychiatric disorders (We do not exclude participants with common comorbidities of dyslexia, specifically dyscalculia, Attention Deficit/Hyperactivity Disorder, or Autism Spectrum Disorders)

History of any acquired brain damage or evidence of fetal alcohol syndrome

Hearing problems and vision problems that cannot be corrected

Inability to follow procedures or understand the instructions given in (Swiss-)German

Trial design

Treatments tested in this trial

  • Transcranial random noise stimulation
  • Sham Stimulation

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Silvia Brem

Lead sponsor

Psychiatric University Hospital, Zurich

Sponsor institution

Swiss National Science Foundation

Collaborator