Gastric outlet obstruction (GOO) occurs commonly in malignancies involving the periampullary region (cancers originating in the head of the pancreas, duodenum, bile duct, or ampulla) or the distal stomach. GOO not only causes debilitating symptoms such as nausea, vomiting, inability to tolerate oral intake, and prevents adequate nutritional intake. Therefore, providing therapy for GOO is imperative to improve the quality of life, and nutritional status of these patients, as well as allow them to continue receiving their cancer treatment
Periampullary malignancy (pancreas, bile duct, ampulla, duodenum) extending to the distal duodenum (D3) or distal (antrum) gastric cancer
post prandial vomiting,
abdominal pain,
inability to tolerate PO,
Age< 18 years old
Pregnancy
Intestinal obstruction distal to the Ligament of Treitz
Evidence of other luminal strictures of the GI tract
Northwell Health
Lead sponsor
Rutgers, The State University of New Jersey
Collaborator