Enucleation Ratio as a Novel Predictor of Symptomatic Improvement After HoLEP

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age18+
SponsorOndokuz Mayıs University

About this trial

The goal of this observational study is to determine whether the rate of prostate tissue removed during surgery relative to the preoperative total prostate volume (referred to as the "enucleation ratio") predicts symptomatic improvement 3 months after HoLEP. The main question it aims to answer is:

\- What is the minimum enucleation ratio required to achieve clinically important symptomatic improvement? (Symptomatic improvement is referred to as a threshold of having an International Prostate Symptom Score (IPSS) lower than 8 points, which is determined by the American Urological Association (AUA) and European Association of Urology(EAU)).

Eligibility criteria

Qualifiers

Men aged 18 years pr older who are planned to undergo HoLEP.

Participants who are willing to give informed consent.

Participants who have moderate to severe LUTS (referring to IPSS score 8 points or more).

No history of previous prostate or urethral surgery.

Disqualifiers

Unwillingness to provide informed consent.

Unwillingness to provide contact information or unreachability during follow-up periods.

Incidental diagnosis of a urogenital malignancy requiring primary treatment after enrollment (e.g., bladder tumor, renal cell carcinoma, testicular tumor).

Trial design

Treatments tested in this trial

  • Holmium laser enucleation of prostate (HoLEP)

Treatment groups

400 Participants
are divided into 1 treatment group

Sponsors and collaborators