EOI Block vs. TAP Block in Minimally Invasive Hepatectomy

ConditionHepatectomy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-80
SponsorSeoul National University Hospital

About this trial

This study aims to compare the analgesic efficacy of two different ultrasound-guided nerve blocks-the External Oblique Intercostal (EOI) block and the Subcostal Transversus Abdominis Plane (TAP) block-in patients undergoing minimally invasive hepatectomy. All participants will receive standardized general anesthesia and perioperative care at Seoul National University Hospital. Following anesthesia induction, patients will be randomly assigned to receive either an EOI block or a subcostal TAP block with 0.375% ropivacaine to provide regional pain relief. Postoperative pain will be managed using a combination of scheduled non-opioid analgesics and a fentanyl-based patient-controlled analgesia (PCA) device. The primary objective is to evaluate which regional technique more effectively reduces cumulative opioid consumption during the first 24 hours after surgery. Additionally, the study will assess pain intensity using the Numerical Rating Scale (NRS), the incidence of postoperative nausea and vomiting, and the overall recovery profile, including the time to first ambulation.

Eligibility criteria

Qualifiers

None

Disqualifiers

American Society of Anesthesiologists physical status IV or higher

History of chronic pain or current use of analgesics, antidepressants, or anticonvulsants for pain management

Known hypersensitivity to general anesthetics, opioids, or local anesthetics

Conversion to open hepatectomy

Trial design

Treatments tested in this trial

  • External Oblique Intercostal Block
  • TAP Block

Treatment groups

140 Participants
are divided into 2 treatment groups