Epileptogenic Network Visualisation With Advanced MRI

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age3+
SponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain

About this trial

The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient.

The investigators aim to compare epileptogenic network identification with stereo-EEG (used as glod standard) with the identification of the same network using advanced MRI (rs-fMRI, microstructural analysis of white matter, ...). The main goals are to:

1. Compare the accuracy of network identification. 2. Analyse the effect of the MRI sequences on candidates selection and target identification.

Participants will already have been selected for stereoEEG and will undergo a supplementary MRI (about 1h) with the additional MRI sequences. Follow-up MRI are scheduled for patient undergoing a second, therapeutic epileptic surgery.

Eligibility criteria

Qualifiers

Patient suffering from drug-resistant epilepsy

Patient already selected for SEEG implantation as part of their epileptic networks

Disqualifiers

Patient excluded from SEEG (pregnant women, children too young for the procedure, patient unable to undergo the procedure)

Contra-indication for MRI

Trial design

Treatments tested in this trial

  • Advanced MRI

Treatment groups

80 Participants
are divided into 1 treatment group