Erector Spinae Block Versus Combined Pecto-intercostal and Recto-intercostal Fascial Plane Block in Cardiac Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-65
SponsorTanta University

About this trial

The aim of this study is to compare the analgesic effects of ultrasound-guided bilateral erector spinae plane block versus ultrasound-guided bilateral combined Pecto-intercostal fascial plane block and recto-intercostal fascial plane block in patients undergoing cardiac surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age from 21 to 65 years.

Both sexes.

Scheduled for open heart surgery with cardiopulmonary bypass and midline sternotomy.

Disqualifiers

History of chronic pain or Long-term or recent use of opioids.

History of allergy to local anesthetic drugs.

Ejection fraction of left ventricle less than 30%.

History of psychiatric diseases or any neurological disorders.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Erector spinae plane block

    Drug

    The block will be done under ultrasound guidance using 20 ml bupivacaine 0.25% that will be injected for each side ensuring not to exceed the maximal 2 mg/kg bupivacaine dose.

  • Combined Pecto-intercostal and recto-intercostal fascial plane block

    Drug

    The blocks will be done under ultrasound guidance using 10-15 ml of 0.25% bupivacaine that will be injected for each side ensuring not to exceed the maximal 2 mg/kg bupivacaine dose..

Treatment groups

66 Participants
are divided into 2 treatment groups
Group A: Erector spinae plane block groupActive comparator 1 intervention
Group B: Combined Pecto-intercostal and recto-intercostal fascial plane block groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

The total opioid consumption in first 24 hours after surgery.

opioid analgesia will be given if the pain scores ≥ 4.

Time frame
24 hours after surgery.

Secondary outcomes

1

Intraoperative fentanyl dose

Fentanyl bolus dosages of 2μg/kg IV will be administered if heart rate or mean arterial blood pressure elevated more than 20% of the baseline.

Time frame
Until the end of surgical procedure.
2

Postoperative pain scores after extubation, at 8, 12, 18, 24, 36, and 48 hour after surgery.

Numerical rating scale pain score (NRS) ranges from 0= no pain to 10= worst pain will be used to evaluate pain scores after surgery.

Time frame
48 hours after surgery.
3

Extubation time

Time from intensive care unit admission until successful removal of endotracheal tube will be recorded.

Time frame
24 hours after surgery.
4

Side effects

Hypotension , bradycardia, postoperative nausea and vomiting

Time frame
24 hours after surgery.

Other outcomes

Sponsors and contacts

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