Ethanol Induces Skeletal Muscle Autophagy
ConditionAlcoholic Liver Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorThe Cleveland Clinic
About this trial
In this study we plan to demonstrate that ethanol induces skeletal muscle autophagy to degrade MAA adducts.
Eligibility criteria
Qualifiers
clinical, biochemical, imaging criteria and liver biopsy where available
Age 18 - 65 years old
Serum liver transaminases (i.e. ALT and AST) 40 IU/L
Normal liver ultrasound
Disqualifiers
Poorly controlled diabetes mellitus (HbA1C>9.5 g/dl)
Untreated Hyper- / hypo- thyroidism
Patients on dialysis, renal disease with serum creatinine 1.5 mg/dL
Active intravenous drug use
Trial design
Treatments tested in this trial
- Biopsies
Treatment groups
40 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov