About this trial
SENIOR transplant Registry European transplant registry of senior renal transplant recipients (above the age of 65 years) receiving initial immunosuppression with tacrolimus once daily, mycophenolate and steroids to investigate long term outcomes on an observational basis.
Eligibility criteria
Qualifiers
Males or females, aged ≥65 years
Patients who received a renal allograft
Patients who are willing and able to participate in the study and from whom written informed consent has been obtained
Patients on an intended standard triple therapy with tacrolimus once daily (Advagraf with trough level ≥5ng/ml) in combination with mycophenolate (either ≥1.0g/day MMF or ≥720mg/d EC-MPS) and Steroids (≥5mg prednisolone or equivalent)
Disqualifiers
Multi-organ recipients (solid organ or bone marrow)
More than secondary renal allograft recipients
Blood group A,B,O-incompatible allografts
Documented presence of donor specific antibodies (DSA)
Trial design
Treatments tested in this trial
- Tacrolimus once daily (Advagraf)
Treatment groups
Locations
Sponsors and collaborators
Klemens Budde
Lead sponsor
Charite University, Berlin, Germany
Sponsor institution
Dr. med. univ. L. J. Lehner
Collaborator
Charite University, Berlin, Germany
Collaborator
ERA-EDTA
Collaborator
DESCARTES Working Group On Transplantation
Collaborator
European Kidney Transplant Association (EKITA)
Collaborator