ELIMINATE is a cohort study, phase 2A, designed to determine whether a standardized microsurgical procedure to evacuate spontaneous lobar intracranial hemorrhage (ICH) is feasible, safe and surgically efficacious in achieving a postoperative residual ICH volume \<15cc on 24-hour postoperative CT imaging.
• Adults > 18 years
CT evidence of acute, spontaneous lobar ICH defined as located <1cm from the cortical surface
ICH volume is >30cc but <80cc as measured by (length x width x height)/2
GCS 5-14 at presentation
• Underlying secondary etiology (AVM, tumor, etc. if known or identifiable acutely)
Intraventricular extension estimated to involve >50% of the lateral ventricle
Preoperative disability that will affect outcome as measured by modified Rankin Scale score (mRS>1 at baseline)
Individuals presenting with GCS <5 at presentation
Dr. Michael D Hill
Lead sponsor
University of Calgary
Sponsor institution
University of Calgary
Collaborator