Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKeck School of Medicine of USC

About this trial

This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as antiretroviral therapy (ART), can be complex to manage because the right regimen depends on many factors-such as drug resistance, other health conditions, and medication schedules. Many people with HIV are cared for by general clinicians who may not have access to HIV specialists, which can make treatment decisions more challenging.

In this study, healthcare providers will use patient cases to compare standard HIV treatment resources with a new clinical decision support tool that gives evidence-based ART recommendations at the point of care.

The investigators hypothesize that using the tool will help providers select treatment plans that better match clinical guidelines, make decisions faster, reduce mental effort, and increase overall satisfaction with the prescribing process.

Eligibility criteria

Qualifiers

Documented HIV-1 infection

Greater than 18 years of age

Genotype resistance testing previously conducted or scheduled through clinical care

Disqualifiers

None

Trial design

Treatments tested in this trial

  • smART (Smart Antiretroviral Therapy Assistant)
  • Traditional Prescribing resources

Treatment groups

250 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Keck School of Medicine of USC

Lead sponsor

Los Angeles General Medical Center

Collaborator

AIDS Healthcare Foundation

Collaborator