Evaluating the Impact of Different Methods of HPV DNA Testing for Cervical Cancer Screening in Primary Care Settings

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age30-69
SponsorNational Healthcare Group Polyclinics

About this trial

Primary objective of the study is to determine the extent that offering of self-sampling in addition to clinician-sampling Human Papillomavirus (HPV) DNA testing will increase detection of HPV DNA through an increase in uptake rates of cervical cancer screening as compared to offering clinician-sampling HPV DNA testing alone.

The hypothesis is that offering additional self-sampling will increase the detection of high-risk HPV DNA by at least 7.7%.

Eligibility criteria

Qualifiers

30-69 years old female Singapore citizens

Due for cervical cancer screening

Engaged in sexual intercourse before

Able to give informed consent

Disqualifiers

Virgo intacta

Pregnancy

History of cervical cancer, precancerous cervical lesions and total hysterectomy

Trial design

Treatments tested in this trial

  • Self-sampled HPV DNA testing
  • Clinician-sampled HPV DNA test

Treatment groups

650 Participants
are divided into 2 treatment groups

Sponsors and collaborators

National Healthcare Group Polyclinics

Lead sponsor

National Healthcare Group, Singapore

Collaborator

KK Women's and Children's Hospital

Collaborator