Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorShady Grove Fertility Reproductive Science Center

About this trial

This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis.

Key Information:

This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer.

Participation remains completely voluntary, and your decision will not affect your current or future care.

We deeply appreciate your support and commitment to advancing fertility research.

Eligibility criteria

Qualifiers

Having ≥ 1 embryo classified as whole chromosome chaotic or complex aneuploid of 3 or more chromosomes following preimplantation genetic testing for aneuploidy using an NGS based platform Signed informed consent

Disqualifiers

Embryos not meeting complex/chaotic criteria Patients declining consent

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

280 Participants
are grouped into 1 trial group