About this trial
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars. The study aims to answer the following:
Does packing CGF Gel into the extraction site improve bone density? Does the use of CGF Gel reduce postoperative pain for the patient? Researchers will evaluate the healing outcomes of patients receiving this treatment in a prospective case series study. Because this is a case series, all participants will receive the CGF Gel intervention rather than being compared to a placebo group.
Participants in this study will:
Undergo a blood draw to create the autologous CGF Gel from their own growth factors.
Undergo the surgical extraction of an impacted lower third molar under local anesthesia.
Have a CGF Gel placed in the extraction socket immediately following the tooth removal. Report their pain levels using a numeric scale on Day 1, Day 3, and Day 7 after surgery. Return for a follow-up CBCT scan three months after the procedure to evaluate bone density changes.
Eligibility criteria
Qualifiers
Patients aged 18 years or older .
Both male and female patients .
Patients requiring odontectomy of an impacted lower third molar .
Disqualifiers
Patients who are pre-surgically symptomatic .
Use of medications that affect bleeding time or bone remodeling .
Patients with a history of radiotherapy or chemotherapy .
Patients who are pregnant or lactating .
Trial design
Treatments tested in this trial
- Concentrated Growth Factor (CGF) Gel