The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) plugs help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
The study aims to answer the following:
Does packing CGF plugs into the extraction site improve bone density? Does the use of CGF plugs reduce postoperative pain for the patient?
Researchers will evaluate the healing outcomes of patients receiving this treatment in a prospective case series study. Because this is a case series, all participants will receive the CGF plug intervention rather than being compared to a placebo group.
Participants in this study will:
Undergo a blood draw to create the autologous CGF plug from their own growth factors.
Undergo the surgical extraction of an impacted lower third molar under local anesthesia.
Have a CGF plug placed in the extraction socket immediately following the tooth removal.
Report their pain levels using a numeric scale on Day 1, Day 3, and Day 7 after surgery.
Return for a follow-up CBCT scan three months after the procedure to evaluate bone density changes.
Patients aged 18 years or older
Both male and female patients
Patients requiring odontectomy of an impacted lower third molar
Patients who are pre-surgically symptomatic
Use of medications that affect bleeding time or bone remodeling
Patients with a history of radiotherapy or chemotherapy
Patients who are pregnant or lactating