In assisted reproductive technology (ART), sperm preparation aims to select the most viable sperm for ICSI. Unlike conventional methods like density gradients or sperm washing, microfluidic techniques mimic natural selection in the female reproductive tract by using laminar flow without centrifugation, reducing the risk of DNA damage. This method isolates highly motile sperm while filtering out debris and immotile cells. Studies show that microfluidics improve embryo quality, increase pregnancy rates, and may lead to higher euploidy rates. Additional benefits include improved safety, scalability, and shorter preparation times.
Women with at least 8 MII per cycle after denudation (AFC≥8).
Women of all ages.
All embryo qualities ≥BL3CC at the time of biopsy on day 5, 6 and/or 7.
Fresh sperm used from ejaculate with a concentration ≥1 mill/ml and ≥10% motility (A+B).
Frozen oocytes samples with severe oligospermia (≤1mill/ml).
PGT-M cases
Sperm with > 1M/ml of round cells