About this trial
The goal of this clinical trial is to evaluate whether a dimensional adaptation of Good Psychiatric Management (called GPM-extended) is more effective than classic Good Psychiatric Management (GPM) in treating adult patients with borderline personality disorder (BPD). Briefly, the GPM-extended model integrates elements from existing adaptations of GPM for narcissistic and obsessive-compulsive personality disorders. It aims to provide a more personalized and dimensional approach to treatment, tailored to each patient's specific personality dysfunction and interpersonal triggers.
The main questions it aims to answer are:
* Does GPM-extended improve overall BPD symptom severity more than classic GPM after one year of treatment? * Does GPM-extended lead to better outcomes in related clinical domains (e.g., personality functioning, emotional regulation, social functioning...) ?
Researchers will compare two groups:
* Patients treated in a center using the GPM-extended program. * Patients treated in a center using the classic GPM program. In each group, patients will receive weekly outpatient psychiatric care for one year.
In terms of evaluation, patients will be evaluated at baseline, 4 months, 8 months, and 1 year. They will undergo both clinician-administered and self-report assessments to measure BPD symptoms and other relevant psychological dimensions.
This study hopes to contribute to the development of dimensional evidence-based treatments for personality disorders.
Eligibility criteria
Qualifiers
Adults (≥18 years old)
Diagnosis of borderline personality disorder according to the SCID-II (≥5 out of 9 criteria)
Provision of written informed consent
Affiliated with or beneficiary of the French national health insurance system
Disqualifiers
Age under 18 years
Presence of a comorbid psychotic disorder, intellectual disability, severe antisocial traits, major substance use disorder incompatible with intensive therapy without abstinence, anorexia nervosa with somatic risk, or bipolar disorder in acute manic phase
Individuals under legal protection (e.g., guardianship or legal safeguard)
Individuals unable to cooperate or complete self- or clinician-administered questionnaires
Trial design
Treatments tested in this trial
- GPM-Extended
- Classic GPM
Treatment groups
Sponsors and collaborators
AddiPsy
Lead sponsor
Clinique Caradoc
Collaborator