About this trial
Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.
Eligibility criteria
Qualifiers
Adult patients (age ≥18 years old)
Paroxysmal or persistent atrial fibrillation, meeting criteria of the 2020 European Society of Cardiology Guidelines for diagnosis and management of atrial fibrillation
Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: Radiofrequency ablation (High power, short duration), Ultra-low temperature cryo ablation, or Pulsed field ablation
Disqualifiers
Known (or suspected) allergic reaction to gadolinium
Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index).
Pregnancy or breastfeeding
Prior intervention in the left atrium (ablation or surgery)
Trial design
Treatments tested in this trial
- Catheter ablation