Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorR&D Cardiologie

About this trial

Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.

Eligibility criteria

Qualifiers

Adult patients (age ≥18 years old)

Paroxysmal or persistent atrial fibrillation, meeting criteria of the 2020 European Society of Cardiology Guidelines for diagnosis and management of atrial fibrillation

Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: Radiofrequency ablation (High power, short duration), Ultra-low temperature cryo ablation, or Pulsed field ablation

Disqualifiers

Known (or suspected) allergic reaction to gadolinium

Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index).

Pregnancy or breastfeeding

Prior intervention in the left atrium (ablation or surgery)

Trial design

Treatments tested in this trial

  • Catheter ablation

Treatment groups

60 Participants
are divided into 3 treatment groups

Sponsors and collaborators