Hereditary spastic paraparesis is a group of inherited neurological diseases. Only symptomatic treatments exist for the moment. The Modifspa study (cf citation) carried out by the team showed that patients perceived a feeling of effectiveness of physiotherapy on lower limb spasticity. The aim of the Walk-up study is to objectivize this feeling of efficacy on gait disorders in these patients.
This is an interventional study using physical training. The study is prospective, open, randomized in 2 parallel groups, one of which is a control group. Analyses will be comparative between the 2 groups during the course of the study.
Patient with molecular diagnosis of hereditary spastic paraparesis based on pathogenic variant of SPAST gene,
Walking possible for 6 minutes without human assistance (one or more technical aids are authorized: e.g. cane, walker, orthoses),
At least 1 physiotherapy session per week already in place.
Understanding of the protocol
Botulinum toxin injection within 2 months of protocol inclusion
Discontinuation of private physiotherapy,
Refusal to participate in the protocol,
Participation in another interventional clinical trial evaluating a health product or in a randomized clinical trial