Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University

About this trial

This study investigates the correlation between ocular biological characteristics and overall conditions before and after liver transplantation by collecting ocular biological characteristics. Explore whether it is possible to construct a clinical prediction model for liver transplantation by incorporating ocular biometric features, in order to optimize disease management before and after liver transplantation.

Eligibility criteria

Qualifiers

Age greater than or equal to 18 years old;

Late stage liver disease patients waiting for liver transplantation treatment, as well as patients with varying degrees of cirrhosis;

Can collect complete basic demographic information, liver function blood test indicators, liver pathology and imaging examination results;

Can cooperate with eye OCT, OCTA and other examinations, and obtain qualified examination parameters;

Disqualifiers

History of other organ transplant surgeries;

History of intraocular laser treatment, medication injection, and surgery;

History of high myopia, glaucoma, and retinal choroidal related eye diseases;

History of major systemic diseases other than liver disease;

Trial design

Treatments tested in this trial

  • Ophthalmic examination
  • General Condition Examination

Treatment groups

500 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Zhongshan Ophthalmic Center, Sun Yat-sen University

Lead sponsor

First Affiliated Hospital, Sun Yat-Sen University

Collaborator

Second Affiliated Hospital, Sun Yat-Sen University

Collaborator

Guangdong Provincial People's Hospital

Collaborator

Nanfang Hospital, Southern Medical University

Collaborator

Zhongshan People's Hospital, Guangdong, China

Collaborator

Guangdong Provincial People's Hospital, China

Collaborator

First People's Hospital of Foshan

Collaborator