Evaluation of Effectiveness and Safety of Antegrade and Retrograde Approach of Percutaneous Coronary Intervention for Chronic Total Occlusions

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19+
SponsorSeung-Whan Lee, M.D., Ph.D.

About this trial

Objective of this study is to 1) analyze the clinical, anatomical and periprocedural differences of patients who underwent a procedure related to coronary CTO through the antergrade approach and retrograde approach; 2) analyze the success rate of the procedures and the incidence and patterns of complications; 3) compare and analyze long-term performances after the successful procedure; and 4) identify the independent factors that require a retrograde approach and the prognostic factor regarding long-term performances after use of each approach.

Eligibility criteria

Qualifiers

Patients aged>=19

Patients who have a CTO lesion in at least one or more epicardial coronary artery 2.5 mm in blood vessel diameter

Patients who have symptoms of angina or objectively proven myocardial ischemia (asymptomatic myocardial ischemia, stable or unstable angina, non - -ST-segment elevation myocardial infarction)

Patients who voluntarily agreed to the protocol and the clinical follow-up plan (or let their representative do this), and signed the informed consent form approved by the IRB of each study institute

Disqualifiers

Patients who are pregnant or lactating or have childbearing potential Patients in whom contrast medium and heparin are contraindicated or who are hypersensitive to them

Patients in whom aspirin, clopidogrel, ticagrelor and prasugrel, cilostazol are contraindicated

Patients scheduled to undergo a surgery, etc. that requires discontinuance of an antiplatelet drug within 12 months after participation in the study

Acute ST elevation myocardial infarction at the time of hospitalization

Trial design

Treatments tested in this trial

  • antegrade and retrograde approach

Treatment groups

4,000 Participants
are divided into 1 treatment group

Sponsors and collaborators

Seung-Whan Lee, M.D., Ph.D.

Lead sponsor

Asan Medical Center

Sponsor institution

Abbott Medical Devices

Collaborator

Teleflex

Collaborator

Medtronic

Collaborator

Dio

Collaborator