About this trial
Objective of this study is to 1) analyze the clinical, anatomical and periprocedural differences of patients who underwent a procedure related to coronary CTO through the antergrade approach and retrograde approach; 2) analyze the success rate of the procedures and the incidence and patterns of complications; 3) compare and analyze long-term performances after the successful procedure; and 4) identify the independent factors that require a retrograde approach and the prognostic factor regarding long-term performances after use of each approach.
Eligibility criteria
Qualifiers
Patients aged>=19
Patients who have a CTO lesion in at least one or more epicardial coronary artery 2.5 mm in blood vessel diameter
Patients who have symptoms of angina or objectively proven myocardial ischemia (asymptomatic myocardial ischemia, stable or unstable angina, non - -ST-segment elevation myocardial infarction)
Patients who voluntarily agreed to the protocol and the clinical follow-up plan (or let their representative do this), and signed the informed consent form approved by the IRB of each study institute
Disqualifiers
Patients who are pregnant or lactating or have childbearing potential Patients in whom contrast medium and heparin are contraindicated or who are hypersensitive to them
Patients in whom aspirin, clopidogrel, ticagrelor and prasugrel, cilostazol are contraindicated
Patients scheduled to undergo a surgery, etc. that requires discontinuance of an antiplatelet drug within 12 months after participation in the study
Acute ST elevation myocardial infarction at the time of hospitalization
Trial design
Treatments tested in this trial
- antegrade and retrograde approach
Treatment groups
Sponsors and collaborators
Seung-Whan Lee, M.D., Ph.D.
Lead sponsor
Asan Medical Center
Sponsor institution
Abbott Medical Devices
Collaborator
Teleflex
Collaborator
Medtronic
Collaborator
Dio
Collaborator