Evaluation of Exercise Testing and Physical Activity in Children and Adolescents Living With Inherited Arrhythmias

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-16
SponsorRoyal Brompton & Harefield NHS Foundation Trust

About this trial

The goal of this observational study is to evaluate exercise testing and daily physical activity in children and adolescents who are diagnosed with an inherited arrhythmia.

The main question it aims to answer is: Does maximum heart rate during controlled exercise tolerance testing accurately reflect maximum heart rate and peak exercise levels during free living daily physical activity in children and adolescents diagnosed with an inherited arrhythmia?

Participants will:

* Complete routine exercise tolerance testing * Record daily physical activity and exercise over two weeks, while wearing an activity and heart rate monitor and digit diary. * Complete a physical activity questionnaire at the end of two weeks.

Eligibility criteria

Qualifiers

Male and female children

Aged 6-16 years

Diagnosed with long QT syndrome or catecholaminergic polymorphic ventricular tachycardia

Treated with beta-blocker and/or sodium channel blockade

Disqualifiers

Children aged less than 6 years

Adults, 17 years of age and above

Unable to run on an exercise treadmill due to physical limitations.

Individuals unable to speak or understand English, due to no translation service available.

Trial design

Treatments tested in this trial

  • Exercise tolerance test
  • Physical activity & heart rate monitoring

Treatment groups

110 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Royal Brompton & Harefield NHS Foundation Trust

Lead sponsor

Great Ormond Street Hospital for Children NHS Foundation Trust

Collaborator

Guy's and St Thomas' NHS Foundation Trust

Collaborator