About this trial
The goal of this observational study is to evaluate exercise testing and daily physical activity in children and adolescents who are diagnosed with an inherited arrhythmia.
The main question it aims to answer is: Does maximum heart rate during controlled exercise tolerance testing accurately reflect maximum heart rate and peak exercise levels during free living daily physical activity in children and adolescents diagnosed with an inherited arrhythmia?
Participants will:
* Complete routine exercise tolerance testing * Record daily physical activity and exercise over two weeks, while wearing an activity and heart rate monitor and digit diary. * Complete a physical activity questionnaire at the end of two weeks.
Eligibility criteria
Qualifiers
Male and female children
Aged 6-16 years
Diagnosed with long QT syndrome or catecholaminergic polymorphic ventricular tachycardia
Treated with beta-blocker and/or sodium channel blockade
Disqualifiers
Children aged less than 6 years
Adults, 17 years of age and above
Unable to run on an exercise treadmill due to physical limitations.
Individuals unable to speak or understand English, due to no translation service available.
Trial design
Treatments tested in this trial
- Exercise tolerance test
- Physical activity & heart rate monitoring
Treatment groups
Sponsors and collaborators
Royal Brompton & Harefield NHS Foundation Trust
Lead sponsor
Great Ormond Street Hospital for Children NHS Foundation Trust
Collaborator
Guy's and St Thomas' NHS Foundation Trust
Collaborator