Caratterizzazione della composizione microbica intestinale nei donatori di FMT e nei pazienti affetti da rCDI al tempo basale e a seguito del trapianto di microbiota fecale. Negli stessi time point valutare il resistoma associato alla comunità microbica rilevata.
patients with rCDI (> 18 years) to whom faecal microbiota transplantation is indicated, without other pathologies or prolonged hospitalization periods
donors: healthy volunteers aged between 18 and 50 years
Patients capable of expressing consent
antibiotic therapies in the last 30 days
treatments with prebiotics - probiotics - postbiotics in the last 60 days
colonization by MDR or XDR pathogens
presence of pre-existing or ongoing intestinal pathologies (Inflammatory Intestinal Diseases, chronic hepatitis, celiac disease, neoplasms, previous large intestinal resections)