Health Trials

Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound

ConditionsPretermVentilator Lung; Newborn
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-24
SponsorAlexandria University

About this trial

This study aims to evaluate the effect of non-invasive ventilation (nIPPV)

, (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates \<37 gestational week with moderate to severe RD using LUS as regard: I. Primary outcomes: Duration of non-Invasive ventilation. II. Secondary outcomes: Evaluation LUS over the 1 st 7 days of life or weaning from ventilation. Need for intubation and invasive ventilation. Duration of respiratory support. Need for surfactant. Oxygen saturation index and oxygen index. Broncho-pulmonary dysplasia; grade. Duration of hospital stay

Eligibility criteria

Qualifiers

None

Disqualifiers

Obvious major congenital abnormalities.

Any of the baby intubated for resuscitation or for other reasons.

Neonates need invasive mechanical ventilation.

Pulmonary hemorrhage.

Trial design

Treatments tested in this trial

  • Nasal humidified heated high flow cannula (NHHHC)
  • Nasal intermittent positive pressure ventilation (NIPPV)
  • Nasal continuous positive airway pressure NCPAP
  • lung ultrasound

Treatment groups

30 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Alexandria University

Lead sponsor

Source ClinicalTrials.gov