About this trial
This study aims to improve understanding of how fetuses respond to oxygen deprivation during labor by re-evaluating cardiotocography (CTG) recordings using a physiology-based interpretation approach and comparing these findings with umbilical cord blood gas measurements at birth, including eucapnic pH assessment.
The study will include term pregnancies and combines retrospective data analysis with prospective enrollment. Researchers will investigate whether physiology-based CTG interpretation can better identify signs of fetal compromise and whether eucapnic pH may improve the distinction between respiratory and metabolic acidosis. Findings may contribute to improving fetal monitoring strategies and the assessment of newborn condition at birth.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Singleton pregnancies
Term neonates (gestational age =or> 37 weeks)
Availability of clinical data, such as
CTG tracing within 90 minutes before delivery
Disqualifiers
Major fetal anomalies
Incomplete or missing CTG or blood gas data
Elective cesarean sections without labor
Trial population
The study population consists of women with term singleton pregnancies undergoing labor and delivery at a tertiary referral center. The study includes both retrospectively identified deliveries and prospectively enrolled pregnancies with available intrapartum cardiotocography (CTG) recordings and umbilical cord arterial blood gas analysis.
Trial design
Cohort
Other
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Detection of fetal decompensation using physiology-based CTG interpretation
proportion of cases in which physiology-based CTG interpretation identified features of fetal decompensation not evident in conventional interpretation
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: