Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorAnkara City Hospital Bilkent
About this trial
This study aims to compare the neuromuscular blockade responses in patients undergoing elective surgery under general anesthesia, with a focus on the use of statins. The study will assess the depth of neuromuscular blockade, recovery time, and postoperative residual curarization using Train-of-Four (TOF) monitoring, with the primary goal of determining whether statin use alters the neuromuscular blockade management.
Eligibility criteria
Qualifiers
Age 18-75 years
ASA classification I, II, III
BMI 18-30
Statin use for at least 3 months or no prior statin use
Disqualifiers
ASA classification IV or higher
BMI <18 or >30
History of liver or renal insufficiency (creatinine >1.6, liver function tests >2x normal)
Neuromuscular, psychiatric, or neurological disorders
Trial design
Treatments tested in this trial
- TOF (Train-of-Four) monitoring for depth of neuromuscular blockade.
Treatment groups
104 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov