This clinical trial is designed to assess the effectiveness of advanced neuromodulation techniques in reducing phantom limb pain by improving sensory feedback in bionic prostheses. The study will explore the use of Peripheral Nerve Stimulation to evaluate their impact on pain relief and sensory restoration. The trial aims the development of neuroprostheses that can provide sensory feedback through stimulation.
Amputation of the upper limb at the level of the forearm or upper arm, or amputation of the lower limb at the level of the lower leg or thigh.
Age between 18 and 65 years.
Duration since amputation is at least 6 months.
Presence of persistent chronic pain syndrome rated between 4 and 10 on the Visual Analog Scale (VAS).
Presence of severe somatic pathology that hinders surgical treatment and participation in the study.
Presence of psychiatric disorders (including a history of), severe depression, suicidal tendencies, or a history of suicide attempts.
Presence of severe orthopedic deformity in the limb above the level of amputation.
History of cancer.
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Treatment groupsSee each treatment group below.
Skolkovo Institute of Science and Technology
Lead sponsor
Motorica LLC
Collaborator
The Federal Center of Brain Research and Neurotechnologies
Collaborator