Evaluation of Right Ventricular Function to Predict Weaning Success in the Intensive Care Unit
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKanuni Sultan Suleyman Training and Research Hospital
About this trial
The goal of this prospective observational study is to evaluate whether right ventricular (RV) function parameters assessed via transthoracic echocardiography (TTE) can predict weaning success in adult intensive care unit (ICU) patients who are mechanically ventilated. The main questions it aims to answer are:
Can the TAPSE (Tricuspid Annular Plane Systolic Excursion) value predict successful extubation?
Do other right heart parameters (tricuspid S', RV-FAC, right atrial area, pulmonary valve acceleration time) provide additional prognostic value for weaning outcomes?
Participants will:
Be adult ICU patients planned for weaning from mechanical ventilation.
Undergo transthoracic echocardiography within 2 hours after meeting clinical weaning criteria.
Have the following echocardiographic parameters measured: TAPSE, tricuspid S', RV-FAC, right atrial area, and pulmonary valve acceleration time.
Be monitored for 24 hours after extubation to assess weaning success (defined as no need for reintubation, non-invasive ventilation, or high-flow oxygen support).
Eligibility criteria
Qualifiers
Receiving invasive mechanical ventilation in the ICU
Planned extubation (weaning) according to standard clinical criteria
Hemodynamically stable at the time of transthoracic echocardiography (TTE)
Ability to undergo echocardiographic assessment within 2 hours prior to extubation
Disqualifiers
Known severe tricuspid valve disease or congenital heart disease
Moderate to severe pericardial effusion or cardiac tamponade
Inadequate acoustic window for transthoracic echocardiography
Patients requiring urgent or unplanned extubation
Trial design
Treatments tested in this trial
- Transthoracic Echocardiography (TTE)
Treatment groups
60 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov