Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-75
SponsorBiocoz Global Pte. Ltd.

About this trial

This is an exploratory, cosmetic-use study evaluating the effects of Super Protein Multifunction (SPM™), a topical peptide-based formulation, on skin appearance, hydration, and barrier-related characteristics in healthy adults. The study aims to collect preliminary biophysical and histologic data on cosmetic skin changes following six weeks of SPM™ use. Participants will apply the product to a designated skin area while a matched contralateral area serves as the untreated comparison site. Skin hydration, transepidermal water loss (TEWL), and tissue markers of skin structure and barrier integrity will be assessed before and after product use. The study includes noninvasive measurements and small punch biopsies at two timepoints.

Eligibility criteria

Qualifiers

Generally healthy with no systemic or active dermatologic diseases.

Willing and able to apply topical product daily for 6 weeks.

Able to provide written informed consent.

Willing to undergo skin biopsies and follow study procedures.

Disqualifiers

History of skin cancer or other malignancy within the past 10 years.

Active or chronic dermatologic conditions (e.g., eczema, psoriasis, acne, rosacea).

Known allergy or sensitivity to components of the investigational product.

Current use of systemic corticosteroids or immunosuppressants.

Trial design

Treatments tested in this trial

  • Skin biopsy
  • Corneometer® Measurement
  • Tewameter® Measurement

Treatment groups

10 Participants
are divided into 1 treatment group

Sponsors and collaborators