About this trial
The hypothesis is that renal function will improve following tricuspid valve intervention. A reduction in renal biomarkers is also expected. Furthermore, based on previous assessments, it is anticipated that there will be an improvement in volume status (reduced edema), symptom burden, and physical capacity in patients. Additionally, the study will assess the impact of the intervention on functional parameters such as motor capacity, physical activity, performance of activities of daily living, and ultimately, participation and quality of life.
Eligibility criteria
Qualifiers
Severe symptomatic tricuspid valve insufficiency and referral for TriClip/TricValve screening
Completed 18th year of life
Ability to consent
Able to walk short distances with aids
Disqualifiers
Dialysis-dependent/terminal kidney disease
Inability to comply with study-associated assessments (e.g., existing dementia)
Severe anemia (Hb <7 g/dl)
Tricuspid valve intervention with palliative intent and likely imminent death
Trial design
Treatments tested in this trial
- Transcatheter edge-to-edge repair (TEER)