Evaluation of the Severity of Hepatic Fibrosis by Magnetic Resonance Elastography in the Diagnosis of Endogenous Hypercorticism

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentral Hospital, Nancy, France

About this trial

The main hypothesis of the HEPACORT study is that upon diagnosis of endogenous Cushing's syndrome, significant liver fibrosis may be present, particularly in the most severe forms of Cushing's syndrome.

the HEPACORT study is the first exploratory study to assess the severity of liver fibrosis in patients with Cushing's syndrome or suspected of presenting by Magnetic Resonance Elastography (MRE).

Eligibility criteria

Qualifiers

age ≥ 18 years old;

Person affiliated to a social security scheme or beneficiary of such a scheme;

Person having received complete information on the organization of the research and having signed informed consent;

Person having carried out a preliminary clinical examination adapted to the research.

Disqualifiers

Person having taken corticosteroid therapy for more than 3 months during the 2 years preceding inclusion;

Person having received corticosteroid therapy of shorter duration with discontinuation less than one month before inclusion;

Person having taken anticortisolic treatment for more than 3 months during the 2 years preceding inclusion;

Person with chronic liver disease;

Trial design

Treatments tested in this trial

  • Magnetic resonance elastography (MRE)

Treatment groups

21 Participants
are divided into 3 treatment groups